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ORIGINAL ARTICLES
Year : 2019  |  Volume : 7  |  Issue : 3  |  Page : 151-162

Comparative therapeutic response of instant and incremental oleation (Sadya and Aarohi Snehapana) over hematological and biochemical parameters in healthy volunteers: A pilot study


1 Department of Panchakarma, Mahatma Gandhi Ayurved College, Hospital and Research Centre, DMIMS (DU), Wardha, Maharashtra, India
2 Department of Rachana Sharir, Mahatma Gandhi Ayurved College, Hospital and Research Centre, DMIMS (DU), Wardha, Maharashtra, India

Correspondence Address:
Dr. Gaurav R Sawarkar
Department of Rachana Sharir, Mahatma Gandhi Ayurved College, Hospital and Research Centre, DMIMS (DU), Salod (Hirapur), Wardha 442001, Maharashtra.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JISM.JISM_66_19

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Introduction: Snehapana (oleation) is the prerequisite treatment for the purification in Panchakarma. Internal oleation therapy is essential for the Dosha migration in the body. So, to identify the effectiveness of instant oleation with incremental as well as safety nature of intervention, the pilot study was planned. Materials and Methods: The study was randomized, parallel group, controlled trial. Participants eligible for internal oleation were included in the study, having age in-between 20 and 40 years. Plane cow ghee was the intervention for both groups. The only difference was in dose pattern. In Group A, 150mL cow ghee with rock salt as used instant administration, whereas in Group B, administration was carried out in incremental dose from 30mL to maximum 210mL (up to the appearance of proper oleation features). Fifteen participants were recruited in each group. Randomization was carried out with simple block method. Objective: The pilot study was intended to measure the hematological and biochemical changes appearing after Snehapana (internal oleation). Outcome: The primary trial objectives of the study were to evaluate therapeutic response of internal oleation in instant and incremental manner and to find out effective modality in vogue. Secondary outcome was to assess safety for the consumption of cow ghee in large amount, which is not good as pretended by contemporary science. Conclusion: Intended primary outcome was not possible to attain because of small sample size. But significant results were obtained in some parameters such as blood urea, serum bilirubin, total bilirubin, serum triglyceride, serum glutamic-pyruvic transaminase, and very low-density lipoprotein (P < 0.05) but within normal range, and the intervention in both were safe in nature, none of the participants had developed any harm in the study. Further clinical trial is suggested for large sample size.


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