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EDITORS NOTE
Journey of Journal of Indian System of Medicine
Srihari Sheshagiri
January-March 2019, 7(1):1-2
DOI:10.4103/JISM.JISM_34_19  
  371 82 -
EDITORIAL
Evidence-based Ayurveda: Way forward......
Ramesh B Devalla
January-March 2019, 7(1):3-4
DOI:10.4103/JISM.JISM_29_19  
  350 64 -
REVIEW ARTICLES
A critical analysis of Raktadhara Kala in perspective of Acharya Sushrut
Deepali M Giri, Namrata B Chouragade
January-March 2019, 7(1):28-32
DOI:10.4103/JISM.JISM_8_19  
Literature of Ayurveda contain a treasure of concepts. Many Ayurveda scholars and experts are continuously working on various concepts. Still the scope of research seems to be unending. Some topics have been studied lesser and Kala Sharir (membranous structures in body) is one of them. Though many people have worked a lot on this topic, we wanted to concentrate on the basic concept of Raktadhara Kala (a fine membrane that lines the blood vessels) and its relation with Mool Sthana of Raktavaha Strotasa (vital component of the Raktavaha Strotasa). We have tried a critical analysis of the concept of Raktadhara Kala described by Acharya Sushruta. The concept is studied in conjunction with the study of histology. A thorough literary study of Samhitas has been done. The histological aspect of the tissues that has similarity with Raktadhara Kala and with the Mool Sthana of Raktavaha Strotasa (a system that is related to circulation, production of blood) was also studied. According to Ayurveda, Strotasa (a system of channels) play an important role in a person’s health. Strotovikriti (abnormality in system of channels) lead to diseases. Kala and Strotasa are closely related. If we could correlate the Kala and Strotasa with the tissues, it will be helpful in diagnosis and treatment of many ailments.
  333 45 -
EDITORIALS
How Ayushman Bharat can be a boon in uplifting ancient AYUSH medical wisdom
Shyam Bhutada
April-June 2019, 7(2):63-65
DOI:10.4103/JISM.JISM_51_19  
  300 55 -
ORIGINAL ARTICLES
In vivo anticancer activity and toxicity of Ayurveda compound W.S.R. to leukemia
Monika Sharma, Sharad Porte, Sandeep Charak
January-March 2019, 7(1):20-27
DOI:10.4103/JISM.JISM_2_19  
Introduction: A diseased caused by an uncontrolled division of abnormal cells in any tissue of any organ of the body is called cancer. There are various types of cancers on the basis of primary abnormal growth in tissues. Leukemia is a type of cancer of blood, which is caused by the rapid production of abnormal white blood cell. In Ayurveda, the reference of the cancer and blood cancer is found indirectly under the heading of Arbuda (cancer) and Rakta Arbuda (leukemia), respectively. In Ayurveda, there are so many herbo-mineral drugs that are useful in treating cancer. Aims and Objectives:
  1. To study the in vivo anticancer (blood cancer) activity of Ayurveda compound.
  2. To compare the toxicity of Ayurveda compound with injection/tablet arsenic trioxide.
  3. To evaluate, elaborate, and discuss the etiology of leukemia as per Ayurveda.
Materials and Methods: An in vivo study was conducted in Institute of Biomedical and Industrial Research. The in vivo antileukemic effect was carried out by using benzene-induced (carcinogen) model in Swiss albino mice and the acute toxicity study was conducted according to fixed single-dose toxicity. The herbo‑mineral drugs has been prepared by using purified arsenic (arsenic trioxide), Vinca rosea, and Urginia indica to study in vivo anti-leukemic effect and toxicity. This study was conducted according to organisation for economic co-operation and development Guidelines 423 and the antileukemic activity was carried out by benzene-induced leukemia in albino mice after animal ethical clearance. Result: The highest dose of the test drug (2000mg/kg) in the acute toxicity study shows minimal adverse effect of toxicity on liver and no adverse effect was found on kidney and spleen. The result was found better in study group 1 having myelocytic leukemia than study group 2 having lymphocytic leukemia. Conclusion: The effect of study drug shows good antileukemic activity, although standard drug was found better than study drug. Overall, the study was found safe and effective on blood cancer.
  274 66 -
REVIEW ARTICLES
Review on role of Agnikarma in pain of various musculoskeletal disorders
Natasha A Rathod, Vaishali V Kuchewar
January-March 2019, 7(1):43-46
DOI:10.4103/JISM.JISM_7_19  
Pain is the cardinal feature of most of the musculoskeletal disorders. Pain is the factor for which patient generally approaches a doctor. Pain is defined as “an unpleasant sensory and emotional experience, which is generally associated with actual or potential tissue damage.” It can affect the quality of life; hence, its preventive measures are of prime importance in health care. In Ayurveda, the word “pain” can be correlated with Ruja, which is caused due to vitiation of Vata. Use of heat therapy for various ailments was found in Ancient Ayurveda treatises. There are different treatment modalities in Ayurveda, which are described by acharyas, Agnikarma (heat therapy) is one among them. Acharya Sushruta has mentioned use of Agnikarma in various disorders such as Granthi (tumor), Arsha (hemorrhoids), Bhagandar (fistula), Arbuda (tumor), Shlipad (filariasis), Antra Vrana (internal injury), and Nadi Vrana (sinuses) in detail. There are different materials that are used, such as Pippali (Piper longum), Aja Shakrut (goat excreta), Godanta (gypsum), Shara (arrow), Shalakha (metal rod), Kshaudra (honey), Guda (jaggery), and Sneha (oil/fat), for giving Agnikarma to various parts of the body such as skin, muscles, blood vessels, and ligaments. As Agnikarma is a parasurgical procedure, Acharya Charak has not described it in separate chapter but has described it as one of the treatment measures in different Vatavyadhis (neuromusculoskeletal disorders) such as Gridhrasi (sciatica). If the drugs such as nonsteroidal anti-inflammatory drugs, which are generally used for relieving pain factor in musculoskeletal disorders, are used for longer duration they can cause potential side effects on the body; hence, there is an emerging need to search for a safe option for the same. In this article, an attempt has been made to search the researches conducted on Agnikarma related to musculoskeletal disorders to establish its role in musculoskeletal pain.
  295 44 -
CONFERENCE REPORTS
“Vatsalyam”—National conference on mother and child health care through Ayurveda
Srihari Sheshagiri
January-March 2019, 7(1):56-58
DOI:10.4103/JISM.JISM_1_19  
  291 39 -
ORIGINAL ARTICLES
Experimental study on effect of Naga Bhasma (lead calx) on hematological and biochemical parameters
Dhirajsingh S Rajput, Nilesh Mahakal, Biswajyoi J Patgiri
January-March 2019, 7(1):8-19
DOI:10.4103/JISM.JISM_9_19  
Background: In recent decade, a lot of concerns has been raised regarding heavy metal content in Ayurveda medicines, especially Bhasma (metallic calx). Naga Bhasma (lead calx) is of the metallic preparation primarily indicated in treating chronic ailments such as Kamala (jaundice), Vatarakta (gout), Grdhrasi (sciatica), Kustha (skin diseases), and Prameha (diabetes). As being a compound of lead, its chronic toxicity study was planned to find out the effect of Naga Bhasma on serum biochemical and hematological parameters. Material and method: Naga Bhasma was prepared by Parada (mercury) and Gandhaka media (NBP) and Vasa Swarasa (juice of Adhatoda vasica Linn.) as herbal media (NBH) in seven Puta (incineration cycles). Chronic oral toxicity study was carried out as per Organization for Economic cooperation and Development (OECD) 408 (90-day oral repeated dose toxicity study). Wistar strain albino rats (Rattus norvegicus) were used for the experimentation. The study was conducted at three dosage levels, therapeutically effective dose (TED) of NBP and NBH was 45 mg/kg body weight of rat, TED × 5 and TED × 10. On 91st day, blood was collected by supraorbital puncture with the help of microcapillary tubes under mild ether anesthesia for estimation of serum biochemical and hematological parameters. Observation and results: Among hematological parameters, significant decrease was observed in MCV (Mean corpuscular volume), MCH (Mean corpuscular haemoglobin), and mean corpuscular hemoglobin concentration by NBH-treated group, whereas in biochemical parameters, both test drugs significantly increased BSL (Blood Sugar Level), SGOT (Serum Glutamic-Oxaloacetic Transaminase), and serum ALP (Alkaline Phosphatise) activity. Hematological and biochemical analysis indicates that both test drugs (prepared in seven incineration cycles) were not found completely safe, especially at higher dosage where the drug affected renal and hepatic functions. Conclusion: For the safety purpose, it is suggested that Naga Bhasma prepared in less number of incineration cycles may not be used for therapeutic purpose.
  262 68 -
REVIEW ARTICLES
A review on Lepa Kalpana: An inherent topical formulations described in Sharangadhar Samhita
Mangesh Dhote, Bharat Rathi, Dhirajsingh S Rajput, Rita Dongre
April-June 2019, 7(2):75-82
DOI:10.4103/JISM.JISM_40_19  
Background: Being one of the major texts in Ayurveda herbal pharmaceutics, Sharangadhar Samhita contributes a very significant part in the world of Ayurveda. It is a major book for reference to academicians as well as physicians. It is an ancient text written by Acharya Sharangadhar in fourteenth century. It is divided into three parts, which are called Khanda. The Khanda includes Prathama Khanda (first part)—7 chapters, Madhyama Khanda (second part)—12 chapters, and Uttara Khanda (last part)—13 chapters, that is, total chapters in Sharangadhar Samhita are 32 and comprises 2600 verses. Materials and Methods: In this work, the review of relevant literature of Lepa Kalpana was carried out from Hindi and English commentary on Sharangadhar Samhita by Pandit Durgadutta Shastri and P. Himasagar Murthy, respectively. In Uttara Khanda, 11th chapter is described as Lepadi Vidhi Adhyaya (chapter on topical dosage formulations) and the same chapter was considered for review. Observation and Results: Total 94 types of Lepa formulations are narrated, of which 80 Lepa formulations contain herbal ingredients, whereas remaining 14 formulations contain herbo-mineral ingredients. Most of these formulations are indicated in skin disorder, hair disorder, migraine, abscess management, anti-inflammatory, and so on. Conclusion: Under the heading of Lepa, Acharya Sharangadhar has provided medicament for local application in common skin diseases. There is a huge scope for research as well as drug discovery and development in the context of Lepa formulations such as Stana and Lingavriddhikar Lepa (breast and penis enlargement), Kurandaghna Lepa (hydrocele), and Suryavarta Ardhavabhedakahara Lepa, mentioned by Acharya Sharangadhar.
  260 54 -
ORIGINAL ARTICLES
Incidence of fissure-in-ano among night duty workers
Kiran B Khandare, Vasudha S Umate, Pooja P Shrivastav
January-March 2019, 7(1):5-7
DOI:10.4103/JISM.JISM_10_19  
Background: Anal fissure is commonly seen in today’s era. The incidence of fissure is 10% of the total cases attending proctology clinics. Lifestyle has an important impact on anorectal diseases along with improper dietary habits. Aims: To analyse whether there is any relation between night awakening and fissure-in-ano or not, this study was undertaken. Materials and Methods: A total of 100 subjects who were working at night since at least 6 months were selected. A prepared questionnaire was given to the subjects and they were asked to fill it genuinely. Subjects who were having fissure-in-ano were observed and noted. Different groups were formed on the basis of the days of night duty of the employees per week, type of night duty, and dietary habits of the individuals, and assessment was carried out. Observation: Sixty-two subjects were found to have some of the complaints listed in the questionnaire. They were examined. Among those 62 subjects, 43 subjects were diagnosed with fissure-in-ano. Conclusion: The study revealed that 8.68% is the incidence of fissure-in-ano in night duty workers, which is found to be significant.
  246 67 -
REVIEW ARTICLES
Role of Ayurveda therapeutic procedures in prenatal and postnatal care
Sudha Dansana, Sujata Kadam
April-June 2019, 7(2):83-89
DOI:10.4103/JISM.JISM_12_19  
Background: Pregnancy and childbirth are challenging events in women’s life cycle. Throughout this journey very often a mother faces several health issues, discomforts, and complications increasing the risk for her life. To deal with this situation, modern medicine usually needs help of different medical and surgical interventions but not all medicines and surgeries are effective. Ayurveda has advocated ample of therapeutic procedures that can take care of the safety of woman during the course of pregnancy and childbirth. Such procedures are being discussed in this article. Materials and Methods: Selected Ayurveda classics, electronic databases, namely PubMed, Digital helpline for Ayurveda Research Articles, National Centre for Biotechnology information, and so on are searched to compile the evidence of such therapeutic interventions advocated during obstetrical management. Results: Shodhana therapy (bio-purification procedures) is strictly contraindicated during pregnancy. However, Panchakarma (five cleansing methods) such as Basti (therapeutic enema), Nasya (instillation of herbal oils, juices, or powders through the nasal route), and other Upakarmas (allied therapies) such as Parisheka (pouring medicated liquids), Avagahana (Tub bath with herbal liquids) are prescribed in the classics of Ayurveda in the context of Garbhini Chikitsa (pregnancy management), Prasava Paricharya (intrapartum management), and Sutika Paricharya (puerperal management). These ancient methods of treatment procedures are advised to be used moderately with pleasant manner. Conclusion: Specific Panchakarma therapies are useful in achieving and maintaining normal pregnancy and enable normal labor. Various Upakarmas facilitate healthy growth and development of fetus, prevent minor ailments and complications in intrapartum as well as in postpartum phase. Hence, Ayurveda procedures appear to be the most effective remedial measure in preventing obstetrical complications, promoting maternal and child health, and lowering maternal mortality rate.
  261 44 -
CASE REPORTS
Proficiency of Khanduchakka Ghrit in the management of Parikartika: A case report
Suraj V Tichkule, Kiran B Khandare, Pooja P Shrivastav
January-March 2019, 7(1):47-50
DOI:10.4103/JISM.JISM_11_19  
Background: Fissure-in-ano is a common anorectal disease. It is mainly of two types: acute and chronic. Chronic fissure-in-ano is difficult to treat and most of the time, it is associated with sentinel tag, which guards the fissure from healing, resulting in nonhealing ulcer, which calls for surgical intervention. Khanduchakka (Ehretia laevis) is a folklore plant that is used popularly by the tribal people for the healing of the nonhealing ulcers. Using that reference in this research work, Khanduchakka Ghrit was used as a local application for managing chronic fissure-in-ano and its efficacy was evaluated. Materials and Methods: In this case report, a patient with chronic fissure-in-ano was treated by Khanduchakka Ghrit, which was used as a local application, after all the mandatory investigations, and its efficacy was evaluated on the basis of clinical parameters such as pain, bleeding, itching, and healing. Results: The patient showed significant results in the clinical parameters evaluated. She got relief in pain, itching, bleeding per rectum, and fissure within 20 days. Even on follow-up assessment, no signs of recurrence were reported. Conclusion: From the aforementioned case, it was concluded that simply applying Khanduchakka Ghrit over a chronic fissure-in-ano is able to heal it. This study revealed that it not only acts as a Ropana (healing agent) but also acts as a Lekhandravya (scrapping agent), which helps in removing slough present at fissure bed and simultaneously helps in the healing of chronic fissure-in-ano.
  254 44 -
REVIEW ARTICLES
Contribution of text Rasapaddhati in the history of Indian alchemy: A review
Bharat Rathi, Renu Rathi, Santosh Pusadkar
April-June 2019, 7(2):70-74
DOI:10.4103/JISM.JISM_31_19  
Background: Rasapaddhati is a classical Sanskrit text related to Rasashastra, which mainly deals with metals, minerals, and mercurial preparations flourished during the medieval period to achieve Dehavada (attaining long and healthy life by using mercurial preparations) and Lohavada (conversion of lower metals into precious metals such as gold and silver). Later knowledge of Rasashastra extended to the therapeutic application in various diseases. Rasapaddhati is a fifteenth-century alchemical treatise written by Acharya Bindu comprising the personal experiences of the author in the field of alchemy. Aims and Objectives: This work is a humble attempt to summarize the key features of text Rasapaddhati, its contents, and contribution in the development of Indian alchemy. Materials and Methods: A review of Rasapaddhati was performed on Siddhiprada Hindi commentary by Siddhinandan Mishra and published by Chaukhambha Orientalia in 1987. Results and Conclusion: It is written in Shardulvikridit Chhanda and is completed in 236 verses. The key features of Rasapaddhati include the classifications of minerals, metals, precious stones, description of mercury, and its various processes and 49 herbal and herbomineral formulations with therapeutic applications in various diseases.
  252 45 -
Critical review on pharmaceutical prospects of acid formulations described in Ayurveda classics with respect to Draavak Kalpas
Bhagyashree Ratan Jibkate, Bharat Jagdishji Rathi, Anita Santoshrao Wanjari, Dhirajsingh Sumersingh Rajput
January-March 2019, 7(1):33-42
DOI:10.4103/JISM.JISM_18_19  
Rasashastra, the pharmaceutical science, deals mainly with the processing and therapeutic utilization of metals and minerals. It aims at designing novel drugs with better curative attributes at minimum doses. Draavak Kalpas (acid formulations prepared by Ayurveda method) are rarely utilized Ayurveda formulations that claim to have specific therapeutic attributes. In spite of being acid preparation, the convenient form of administration and doses of Draavak Kalpas are more acceptable and can increase its usage to prevent and cure diseases of gastrointestinal tract. Draavak Kalpas are liquid preparations obtained by processing Lavana (salt) and Ksharas (alkaline materials). Forty different formulations, ingredients, methods of preparation, and its indications along with dose and Anupanas (adjuvant) are the peculiarity of this review. Distillation process and application of proper heat is the foremost method to obtain good quality of Draavak. Draavak Kalpas is the specialty of Rasashastra as they are mentioned only in the texts of Rasashastra. This review is carried out for the future research, so that its actual efficacy and utility of indications can be acknowledged.
  238 50 -
EDITORIALS
Samhita-based edification: an incredible primeval Indian medical education system
Bharat C Chouragade
April-June 2019, 7(2):66-69
DOI:10.4103/JISM.JISM_52_19  
  242 40 -
CASE REPORTS
Ayurvedic management of Gridhrasi with special respect to sciatica: a case report
Manju Mohan, Punam Sawarkar
April-June 2019, 7(2):131-138
DOI:10.4103/JISM.JISM_38_19  
Background: Gridhrasi is one of the most common disorders of Vata, which closely resembles with sciatica, which is characterized by pain or discomfort associated with sciatic nerve. The prevalence of sciatica varies considerably ranging from 3.8% in the working population to 7.9% in the nonworking population. Contemporary medicine has limitations giving short-term relief in pain or surgical intervention with side effect. Aim and Objectives: The aim of this study was to access the efficacy of Ayurvedic management including Shodhana and Shamana Chikitsa in Gridhrasi.Materials and Methods: It is a single case study. A 43-year-old man who was already diagnosed with intervertebral disc prolapsed in L4-L5, correlated with Gridhrasi of left leg since 7 months approached to Ayurvedic hospital and was treated with Panchakarma treatment including Dashmooladi niruha vasti, Kati vasti, and Patra panda pottali sweda along with Shamana Chikitsa. The treatment was continued for consecutive one month. Results: Symptomatic assessment of patient was carried out after one month and satisfactory outcome was there and overall quality of life of patient was significantly improved. Conclusion: The aforementioned therapy gives symptomatic relief for the management of Gridhrasi.
  207 29 -
CONFERENCE REPORTS
Kalaanveshan-2019: National conference on “Exploring the concept of Kala and its applicability”
Amol Madhav Deshpande
January-March 2019, 7(1):59-61
DOI:10.4103/JISM.JISM_27_19  
  181 44 -
ORIGINAL ARTICLES
Correlation of Agni with Koshtha, Prakruti, and Mala
Namrata B Chouragade, Deepali M Giri, Bharat C Chouragade
April-June 2019, 7(2):99-103
DOI:10.4103/JISM.JISM_25_19  
Background: Agni (digestive capacity) is an important factor for digestion and metabolism in our body. Ingested food is to be digested, absorbed, and assimilated, which is unavoidable for the maintenance of life, and is performed by the Agni. Agni resides and functions in the body in the form of Pitta (a physiological humor). Wellness and illness of an individual depends on the proper and improper functions of the Agni. Hence, Agni is said to be the Mool (base) of life. Materials and Methods: In this study, 60 healthy volunteers were randomly selected, and their Agni, Koshtha (nature of bowel), Prakruti (physical and mental temperament), and Mala Parikshan (stool examination) were examined through prevalidated Case Record Proforma (CRP), and the results were recorded, and correlation of status of Agni with Koshtha, Prakruti, and Sama-Nirama Mala Parikshan was conducted. Results and Conclusion: The result shows correlation of Agni with Koshtha, Prakruti, and Mala type (Sama and Nirama), which is in tune with the principles described in Samhitas (basic text of Ayurveda), and it is evident that Agni is the most important factor for health as described in the definition of health in Sushruta Samhita.
  187 23 -
CASE REPORTS
A case report on management of recurrent anal fistula by Nyagrodha Ksheer Sutra
Dhananjay D Deshmukh, Kiran B Khandare, Pooja P Shrivastav
January-March 2019, 7(1):51-55
DOI:10.4103/JISM.JISM_16_19  
Background: Fistula in ano is defined as an inflammatory tract lined by unhealthy granulation tissue having its external opening in the perianal region and internal opening in the anal canal or rectum. In Ayurveda, it can be correlated with Bhagandar (fistula in ano). Various surgical as well as para-surgical treatments are in rage to treat anal fistula but have certain limitations and risk of recurrence. Critical recurrent anal fistula is one among the toughest and rare anal fistula to treat and still stand as a challenge in front of surgeons. Materials and Methods: In this case report, critical recurrent anal fistula is managed by Nyagrodha Ksheer (Latex) Sutra (medicated seton) after all the mandatory investigations, and its efficacy was evaluated on the basis of clinical parameters such as pain, itching, pus discharge, and cutting rate. Results: Patient showed significant results in clinical parameters evaluated. Even after 1-month follow-up assessment, there were no signs of recurrence. Conclusion: As seen in many cases, it is very difficult to manage the anal fistula because of its high recurrence rate. In this case also, it was evident that the patient was having the same complaint of recurrence of fistula after multiple surgeries. In order to find out a minimal invasive technique, an attempt was made to treat the critical recurrent fistula with the help of Nyagrodha Ksheer Sutra. From the aforementioned case, it is concluded that Nyagrodha Ksheer Sutra is efficient in treating critical recurrent anal fistula. It also revealed that Nyagrodha Ksheer acts on the basis of its Shodhan (wound cleaning) and Ropan (wound healing) property to heal critical recurrent anal fistula.
  162 47 -
REVIEW ARTICLES
Preconception care in Ayurveda
Revathy Padmakumar Sindhu, Syamlal Sivaramakrishnapillai
April-June 2019, 7(2):90-92
DOI:10.4103/JISM.JISM_5_19  
Reproduction is one of the basic requirements of any species to continue its existence on the universe. Human reproduction includes stage-wise procedures leading to formation of a new individual. Any simple deviation in this finely calculated series of events can lead to the drastic pathological conditions. Ayurveda, the extract of the entire Vedas, dreams about add (good progeny). Human birth process with pre- and post-event knowledge is explained by (Branch which deals with Obstetrics), which is an integrated part of (Branch which deals with Pediatrics). The preconceptional care in Ayurveda was described centuries back to get a disease-free and good progeny by following the regimen and rituals. Recent research shows that each seminal ejaculation in intercourse depletes the body energy of male counterpart, hence to maintain the quality and energy of sperm, (following of celibacy) for one month before (Conception) was planned. The aim of Aharaniyama before conception was to elevate the qualities of sperm and ovum. Garbhadhana and Puthreshti speak about the preparation of mind-set of would-be parents and to evoke a zeal to have a good progeny. Preconception care is an extension of prenatal care to provide optimal health to mother and baby. Thus, this study helps to explore Ayurveda measures to get a Shreyasipraja.
  160 31 -
ORIGINAL ARTICLES
Pharmaceutico-analytical study of Adraka Khanda
Neha S Chavhan, Bharat Rathi
April-June 2019, 7(2):112-118
DOI:10.4103/JISM.JISM_19_19  
Background: Adraka (Zingiber Officinale) Khanda described in Bhaishajya Ratnavali is a drug of choice in Udarda (Pressure Urticaria), Shittapitta (Cold Urticaria) and Koth (Solar Urticaria) such as autoimmune system. This formulation is having spicy test. Khanda being one of the common dosage from appreciated by all age group for their palatability and easy method of administration and feasibility. Pharmaceutical standardization of this formulation is not established yet, which is first step towards research on the formulation. Hence present work was planned. Material and Method: Three batches of Adraka were prepared by adopting reference of Bhaishajya Ratnavali and the average required for preparation of Adraka Khanda was one day. A constant heat of 90 to 100 °C was maintained throughout the procedure. Result and Conclusion: The analytical study revealed average observed values of pH (6.2), Acid insoluble ash (0.50), Moisture content (3.5), Water extract (23.2) Alcoholic extract (20.8), Water soluble ash (4.3) , Total ash (5.2).
  168 20 -
CASE REPORTS
Role of Khanduchakka (Ehretia laevis) Lepan (local application) in the management of delayed union of metatarsal fracture: A case report
Suraj V Tichkule, Kiran B Khandare, Pooja P Shrivastav
April-June 2019, 7(2):127-130
DOI:10.4103/JISM.JISM_26_19  
Background: The application of Khanduchakka (Ehertia Laevis) Kalka (paste) in the case of Delayed-union of metatarsal fracture is an innovative idea. It is a case report having the fracture of 3rd and 4th metatarsal of right foot. Ehertia Laevis is folklore plant locally known as Khanduchakka used in fracture and wound healing in various forms by the tribal people. In the present case it is used as Lepan (local application). Observation after treatment shows that the Ehertia Laevis is an effective alternative treatment for fracture and delayed union of bones without any complications. Aim: To evaluate healing effect of Khanduchakka Lepan in the management of Delayed union of Metatarsal fracture. Material and Method: In this present case report, the patient with Delayed union of Metatarsal fracture was treated with Khanduchakka Kalka used as local application after all the mandatory investigations and its efficacy was evaluated on the basis of clinical parameters like pain, swelling and fracture healing. Statistical analysis used: 1. Universal Pain Assessment Tool i.e. Visual Analog Scale (VAS) scoring for pain. 2. Swelling was assessed by measuring affected foot circumference in centimeters. 3. American Orthopedic Foot and Ankle Scale (AOFAS) result was calculated. Results: Patient showed significance results in clinical parameters evaluated. He got partial relief within 2 weeks. Conclusion: X-Ray revealed that there was callus formation and the mal-union was slightly aligned just by simply applying Khanduchakka Kalka over a fracture. Visual analog scale used for pain showed before treatment score - 8/10 and after treatment score - 2/10. Circumference of swelling reduced from 33cm to 29cm. AOFAS score was improved from 38/100 to 79/100 points. Therefore it can be concluded that this intervention not only acts as fracture healing but also relieved symptoms of pain and swelling.
  160 25 -
ORIGINAL ARTICLES
Comparative organoleptic and physicochemical study of roots of Hemidesmus indicus (L.) R. Br. and Decalepis hamiltonii Wight and Arn
Parul P Nandgaonkar, Pramod Khobragade, Akshay S Pargaonkar, Pradeep S Nandgaonkar
April-June 2019, 7(2):93-98
DOI:10.4103/JISM.JISM_44_19  
Background: Hemidesmus indicus (L.) R. Br. (Sariva), commonly known as Anantmool, is used in therapeutics in Ayurveda with its unique attributes. From few decades due to the heavy demand and extreme commercial collection from natural habitat of this plant, its natural population has decreased with higher rate and has resulted in the extinction of population. In various Ayurvedic raw drug market and in the leading Ayurvedic pharmacies, the roots of Decalepis hamiltonii, which is considered as Sariva Bheda, are used in place of the roots of H. indicus (Sariva) in Ayurvedic formulations. Though H. indicus is cultivated by special method, still it is a very time-consuming and expensive process. D. hamiltonii is easily cultivated with high yield and is less expensive as compared to H. indicus. Aim: In view of these facts, this study was undertaken to compare physicochemical analysis of H. indicus and D. hamiltonii.Materials and Methods: Field samples of H. indicus and D. hamiltonii were collected, identified, authenticated, and studied for vegetative, pharmacognostic, organoleptic, and physicochemical characters. Observation and Results: The root of H. indicus and D. hamiltonii are easily identified by their organoleptic characters. The physicochemical parameters such as loss on drying, total ash, acid-insoluble ash, alcohol-soluble extractives, and water-soluble extractive showed some differences. Conclusion: The external morphological characters of both collected field samples are clearly distinguished and identified as H. indicus (L.) R. Br. and D. hamiltonii Wight and Arn, and they also differ on the physicochemical parameters.
  158 24 -
Effectiveness of mobile app as a teaching and learning tool
Gaurav R Sawarkar, Priti R Desai, Punam G Sawarkar
April-June 2019, 7(2):104-111
DOI:10.4103/JISM.JISM_36_19  
Background: The field of mobile technology in health sciences is somewhat newer concept and provides more openings to future researchers for conduction of more studies. Mobile devices with various applications offer noteworthy facilities with its transportability and accessibility. Rachana Sharir (anatomy) is itself one of the volatile subjects in which various concepts such as Marma Sharir are difficult to understand and memorize. Therefore, to make the topic interesting and easy to comprehend, there is need to make changes in teaching and learning methodology by using Marma Mobile App. Aims and Objectives: This study aimed to assess the efficacy of Mobile App as a teaching and learning tool and perception toward Mobile App, and to compare the efficacy and retention of knowledge in Mobile App and conventional teaching. Materials and Methods: First-year BAMS (Bachelor of Ayurvedic Medicine & Surgery) students were involved in the study. Two modules were prepared on Marma Sharir. Accordingly, pretest and posttest were prepared and conducted before and after teaching the module, respectively. Feedback was noted after crossover study. Observation and Results: The score of posttests was highly significant in Mobile App method as compared with conventional teaching. Students were truly agreeing with Mobile App method and admitted that Marma App developed more interest in the topic and reduced the study duration with increased recall skill. Conclusion: Students remarked that the App was helpful to develop interest in the topic and reduced study duration required for the topic. It created good visual impact and helped in quick recall with retention of knowledge as compared with the conventional teaching. Students suggested for addition of animations and videos in the present App.
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Pharmaceutico-analytical standardization of Yashtimadhvadi Taila prepared from Murchhita and Amurchhita Tila Taila
Ujala P Kale, Anita S Wanjari, Bharat Rathi, Dhirajsingh S Rajput
April-June 2019, 7(2):119-126
DOI:10.4103/JISM.JISM_35_19  
Introduction: Sneha Murchhana is a process carried out on fats and oils before subjecting to preparation of medicated ghee and oils. It can be interrelated to refinement of oil, though there is variation in refinement and Murchhana, that is, Murchhana enhances its concentration of high-density fatty acids, increases efficacy of formulation, and decreases rancidity and undesirable color. The standardization of Yashtimadhvadi Taila is not mentioned in Ayurvedic Pharmacopoeia of India; hence in this study, an attempt has been made to establish pharmaceutical standardization of Yashtimadhvadi Taila prepared from Murchhita and Amurchhita Tila Taila. Materials and Methods: For pharmaceutical standardization of Yashtimadhvadi Taila prepared from Murchhita and Amurchhita Tila Taila, Murchhana of oil was carried out as mentioned in Bhaishajya Ratnavali, and Yashtimadhvadi Taila was formulated as referred in Vaidya Chintamani. In analytical study, the samples were subjected to physicochemical analysis such as refractive index, specific gravity, saponification value, unsaponifiable matter, acid value, iodine value, and peroxide value. Observations: Average quantity obtained after Murchhana of Tila Taila was 94.74%, that is, 5.26% weight loss. Total time required for the preparation of MYT (Yashtimadhvadi Taila prepared from Murchhita Taila) and AYT (Yashtimadhvadi Taila prepared from Amurchhita Taila) was 10h and 8.30h with 7.29% and 5.20% weight loss, respectively. The heating process was finished in three days. After Murchhana, increase in saponification value and decrease in iodine and peroxide value were observed. This suggested that the application of Murchhana process on the base oil (Tila Taila) enhanced the properties and stability of Yashtimadhvadi Taila.Conclusion: Yashtimadhvadi Taila can be prepared in three days by heating and maintaining average temperature up to 100°C. Mild heating and constant stirring are needed for medicated oil preparations possessing desired attributes. Considering all the data of study indicates the importance of concept of Murchhana in the therapeutic potency of Yashtimadhvadi Taila.
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