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ORIGINAL ARTICLE
Year : 2015  |  Volume : 3  |  Issue : 2  |  Page : 60-64

Pharmaceutical Standardization of Shatavari Granules


1 Assistant professor, Dept of Rasashastra and BK, MGACH & RC, Salod (H), Wardha, India
2 Asst. Professor, Dept of Rasashastra and BK, MGACH & RC, Salod (H), Wardha, India
3 Associate Professor, Dept of Rasashastra and BK, MGACH & RC, Salod (H), Wardha, India
4 Professor, Dept of Rasashastra and BK, MGACH & RC, Salod (H), Wardha, India

Correspondence Address:
Rohit Gokarn
Assistant professor, Dept of Rasashastra and BK, MGACH & RC, Salod (H), Wardha
India
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Source of Support: None, Conflict of Interest: None


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Standardization is necessary to maintain batch to batch consistency as well as for repeated preparation of drug on large scale. Modification of ancient dosage forms and development of new dosage forms is a continuous process which has significant contribution in flourishing the science with changing life style and favor of people. Preparation of granules is one of modified form of Ghana (solid preparations of herbal extract) and Khanda Kalpana (solid preparations similar to granules). Shatavari granule is a well known formulation for its beneficial properties such as Stanyajanana (galactagogue), Balya (immuno-modulators), Rasayana (rejuvenator), Amlapittahara (act as antacid in hyperacidity) etc. Present study has elaborated standardization of Shatavari granules. Three batches of Shatavari granules were prepared by adopting reference of Vriddha Vaidya and analyzed as per mentioned in Ayurvedic Pharmacopia of India (API). The average time required for preparation of Shatavari granules was 6.40 hours. A constant heat of 90°C-100°C was maintained throughout the procedure. The analytical study revealed average observed values of Loss on drying (at 105°C), Total ash, Acid Insoluble ash, Alcohol Soluble extractives, Water Soluble extractive, pH, Bulk density and Tap density were 3%, 5.7 %, 0.5%, 25%, 54%, 4.0 (10% aqueous solution), 0.642 gm/ml, 0.810 gm/ml respectively. Particle size of prepared batches was 2 to 4 mm size. Antimicrobial study showed complete absence of any bacterial contamination. Vigilant hygienic care while following every step, temperature for heating and accessing completion stage of procedure are the key points during preparation of Shatavari granules.


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