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Year : 2016  |  Volume : 4  |  Issue : 4  |  Page : 192-195

Comparative screening of intestinal transit time of three available source drugs of Trivrut (Operculina turpethum) in Swice albino mice

1 Research Officer, RARI- UD, Jammu, India
2 Prof & Head, Dept of Dravyaguna, IPGT&RA, GAU, Jamnagar, India
3 Head, Pharmacology Lab, IPGT&RA, GAU, Jamnagar, India

Correspondence Address:
Rasika Kolhe
Research Officer, RARI- UD, Jammu
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Source of Support: None, Conflict of Interest: None

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Effect of the root barks powder of three source drugs of Trivrut i.e. Operculina turpethum, Operculina petaloidea and Marsdenia tenacissima were carried out on intestinal transit time. 40% Kaoline was administered to overnight fasted Swiss albino mice after administration of O turpethum, O petaloidea and M tenacissima in the dose of 650mg/kg. Operculina turpethum which is official botanical source drug of Trivrut showed significant result in decreasing intestinal time followed by Operculina petaloidea indicating some of the working mechanism as increased in intestinal motility of Virechana drug described in Ayurveda, whereas animal treated with M tenacissima did not produce significant changes in comparison to control group.

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