• Users Online: 127
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2020  |  Volume : 8  |  Issue : 3  |  Page : 210-216

Shelf-life evaluation of Indukanta Ghritam: A preliminary study


Department of Rasa Shastra and Bhaishajya Kalpana, All India Institute of Ayurveda (AIIA), New Delhi, India

Correspondence Address:
Dr. Punam Aggarwal
Department of Rasa Shastra and Bhaishajya Kalpana, All India Institute of Ayurveda (AIIA), Mathura Rd, Gautampuri Awas, Sarita Vihar, New Delhi.
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JISM.JISM_77_20

Rights and Permissions

Background: The concept of Saviryata Avadhi (shelf life) of different Ayurveda dosage forms is well described in Sharngadhara saṃhita. Shelf life is an important component and is mandatory to be displayed on the label of all medicinal products. This is also applicable to Ayurveda; thus, it becomes essential to establish shelf life of formulations that are being marketed and used in therapeutics. An attempt has been made in this study to evaluate shelf life of Indukanta Ghritam (IKG) which is not reported till date though in general it has been quoted by Gazette of India, that is, 2 years. Aim: To evaluate the shelf life of IKG through the accelerated stability study. Materials and Methods: Five batches were prepared according to Ayurveda Pharmacopoeia of India and the observations and results were systematically recorded. Physicochemical parameters were measured at the temperature of 40°C ± 2°C and the relative humidity was 75% ± 5%. The analysis was carried out at the intervals of 0, 1, 3, and 6 months, and the average 10% degradation time was calculated and extrapolated to find the shelf life as per ICH guidelines and high-performance thin-layer chromatography (HPTLC) analysis of sample was also carried out. Results: The average percentage loss in final product was 7.71% in IKG. The shelf life of IKG is found to be 19 months. Conclusion: The classics have mentioned the shelf life as 16 months, whereas the Gazette of India states the shelf life as 2 years for Ghrita. The shelf life of IKG is equal to the classic. This might be because of the precautions observed during the manufacturing and storing phases of the drug.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed132    
    Printed8    
    Emailed0    
    PDF Downloaded20    
    Comments [Add]    

Recommend this journal